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Article

Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders.

Molecular psychiatry - 1 Nov 2024

Luo Jie, Li Ling, Niu Mingming, Kong Dehui, Jiang Yi, Poudel Suresh, Shieh Annie W, Cheng Lijun, Giase Gina, Grennan Kay, White Kevin P, Chen Chao, Wang Sidney H, Pinto Dalila, Wang Yue, Liu Chunyu, Peng Junmin, Wang Xusheng

Abstract excerpt

Psychiatric disorders are highly heritable yet polygenic, potentially involving hundreds of risk genes. Genome-wide association studies have identified hundreds of genomic susceptibility loci with susceptibility to psychiatric disorders; however, the contribution of these loci to the underlying psychopathology and etiology remains elusive. Here we generated deep human brain proteomics data by quantifying 11,608...

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Identifiers

PMID: 38724566
DOI: 10.1038/s41380-024-02576-8
PMCID: PMC11540848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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