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Article

Alzheimer's disease reconfigures hippocampal transcriptional responses to surgery: an interaction-based transcriptomic analysis

2026-06-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Perioperative neurocognitive disorders (PND) are clinically important complications after anesthesia and surgery. Alzheimer's disease (AD) pathology is considered a major vulnerability factor, yet it remains unclear whether AD simply amplifies postoperative neuroinflammation or qualitatively reconfigures the hippocampal response to surgery. <bold>Methods:</b...

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Literature Corpus work
f2f86f18-1bf3-5a74-bbe2-ca7a083e614c
DOI
10.21203/rs.3.rs-9887622/v1
Open publication

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Alzheimer's disease reconfigures hippocampal transcriptional responses to surgery: an interaction-based transcriptomic analysisDOI 10.21203/rs.3.rs-9887622/v1
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