Article

Excitation-Inhibition Imbalance Underlies Perioperative Neurocognitive Disorders: A Single-Nucleus Transcriptomic Perspective in Mice Hippocampus

2025-07-27

Abstract excerpt

<title>Abstract</title> <p>Perioperative neurocognitive disorders (PND), highly prevalent in geriatric surgical populations, constitute a major postoperative clinical challenge associated with prolonged hospital stays and adverse surgical outcomes. Although substantial research efforts have been devoted to investigating etiology, the precise molecular mechanisms of PND remains elusive, thereby hindering the devel...

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Literature Corpus work: 4fe077f2-b432-50b5-a9cc-d047aed3c7b7
DOI: 10.21203/rs.3.rs-7067489/v1

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