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Hippocampal transcriptome-wide association analysis of shared genetic risks between posttraumatic stress disorder and Alzheimer’s disease

2025-08-13

Abstract excerpt

The etiopathogenesis of Alzheimer’s disease (AD) is puzzled by the heterogeneous nature of this neurodegenerative disorder. In recent years, clinical and basic research has accentuated a relationship between post-traumatic stress disorder (PTSD) and AD risk. Despite several pathways related to neuroinflammation, metabolic disturbances, and stress, emerging evidence implicates genetic risks at the nexus of PTSD and...

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Literature Corpus work
be39eb06-7ba2-5ad6-a5d7-b0dbd68670b6
DOI
10.1101/2025.08.11.25333445
Open publication

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Hippocampal transcriptome-wide association analysis of shared genetic risks between posttraumatic stress disorder and Alzheimer’s diseaseDOI 10.1101/2025.08.11.25333445
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