Article

Human neural stem cells restore spatial memory in a transgenic Alzheimer’s disease mouse model by an immunomodulating mechanism

2023-11-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> Stem cells are a promising therapeutic in Alzheimer’s disease (AD) given the complex pathophysiologic pathways involved. However, the therapeutic mechanisms of stem cells remain unclear. Here, we used spatial transcriptomics to elucidate therapeutic mechanisms of human neural stem cells (hNSCs) in an animal model of AD. <h4>METHODS</h4> hNSCs were transplanted into the fi...

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Literature Corpus work: a3c251b2-fb0c-5a06-be5f-5241240ff25e
DOI: 10.1101/2023.11.01.565161

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