Article
Transcriptional background effects on a tumor driver gene in a transgenic medaka melanoma model
2022-02-19
Abstract excerpt
The Xiphophorus melanoma receptor kinase gene, xmrk , is a bona fide oncogene driving melanocyte tumorigenesis of Xiphophorus fish. When ectopically expressed in medaka, it not only induces development of several pigment cell tumor types in different strains of medaka, but also induces different tumor types within the same animal, suggesting its oncogenic activity has a transcriptomic background effect. Althoug...
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Identifiers and source
- Literature Corpus work
- f1dec8a1-bc08-5b9a-8adb-09c549a5b434
- DOI
- 10.1101/2022.02.16.480743