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Comparison of Human Melanoma Single Cell Profiles to Evolutionary Medicine Model <i>Xiphophorus</i> Provides Insights In Disease Control

2025-09-24

Abstract excerpt

Melanoma remains one of the deadliest forms of cancer. Despite recent therapeutic advances including immune checkpoint inhibitors and small-molecule kinase inhibitors, patients frequently develop treatment resistance. Novel models are needed to devise strategies that overcome resistance and further reduce melanoma-related mortality. Interspecies hybrid fish from the Xiphophorus lineage develop mutant Epidermal Gr...

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Literature Corpus work
2bf56741-cbf0-5cd4-8891-66fe7389b2c3
DOI
10.1101/2025.09.22.677876
Open publication

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Comparison of Human Melanoma Single Cell Profiles to Evolutionary Medicine Model <i>Xiphophorus</i> Provides Insights In Disease ControlDOI 10.1101/2025.09.22.677876
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