Article

<i>De novo</i> design of a safe and potent respiratory syncytial virus immuno-focusing antigen

2026-01-29

Abstract excerpt

<h4>SUMMARY</h4> Respiratory syncytial virus (RSV) remains the leading cause of severe respiratory infections in infants, the elderly, and the immunocompromised. Although stabilized full-length pre-fusion (pre-F) protein vaccines are promising, enhanced respiratory disease (ERD) remains a critical safety concern. Here, we used artificial intelligence to design a de novo immuno-focused antigen that structurally p...

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Literature Corpus work: f17ca7e5-b215-5ff2-82c7-bdef76eb3c2b
DOI: 10.64898/2026.01.28.702448

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