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Article

Computational redesign of human respiratory syncytial virus epitope as therapeutic peptide vaccines against pediatric pneumonia.

Journal of molecular modeling - 2 Mar 2018

Shi Xiangxiang, Zheng Jun, Yan Tingting

Abstract excerpt

Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections in infants and young children. Here, the RSV fusion (F) glycoprotein epitope FFL was redesigned based on its complex crystal structure with motavizumab, an mAb drug in development for the prevention of RSV infections, aiming to obtain therapeutic peptide vaccines with high affinity to induce RSV-specific...

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Share to Antibodies, Monoclonal, Humanized
Share to Antigen-Antibody Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, Viral

Share to Epitopes

Share to Respiratory Syncytial Virus, Human

Share to Respiratory Syncytial Virus Infections

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Share to Vaccines, Subunit

Source

Identifiers

PMID: 29500665
DOI: 10.1007/s00894-018-3613-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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