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Article

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism.

Nature communications - 3 Sept 2015

Krarup Anders, Truan Daphné, Furmanova-Hollenstein Polina, Bogaert Lies, Bouchier Pascale, Bisschop Ilona J M, Widjojoatmodjo Myra N, Zahn Roland, Schuitemaker Hanneke, McLellan Jason S, Langedijk Johannes P M

Abstract excerpt

Respiratory syncytial virus (RSV) causes acute lower respiratory tract infections and is the leading cause of infant hospitalizations. Recently, a promising vaccine antigen based on the RSV fusion protein (RSV F) stabilized in the native prefusion conformation has been described. Here we report a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26333350
DOI: 10.1038/ncomms9143
PMCID: PMC4569726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26333350-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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