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Serum-derived exosomal circENC1 inhibits SMC phenotypic switching to stabilize atherosclerotic plaques by interacting with miR-513a-5p and inhibiting MYH9 degradation 

2024-06-06

Abstract excerpt

<title>Abstract</title> <p>Introduction: The function of serum-derived exosomes (serum-exos) that suppress smooth muscle cell (SMC) phenotypic switching-related genes in plaque stabilization is unclear. We aimed to determine the functional role of serum-exos, which are pivotal molecular regulators, in plaque stabilization and the underlying mechanism. Methods and results RNA sequencing and bioinformatic analyse...

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Literature Corpus work
f0dbff3b-b9ae-5989-b2d5-bfd35b58e608
DOI
10.21203/rs.3.rs-4461787/v1
Open publication

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Serum-derived exosomal circENC1 inhibits SMC phenotypic switching to stabilize atherosclerotic plaques by interacting with miR-513a-5p and inhibiting MYH9 degradationDOI 10.21203/rs.3.rs-4461787/v1
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