Article

LARP6 Promotes Features of Plaque Stability and Smooth Muscle Cell Survival in Atherosclerosis

2025-12-25

Abstract excerpt

<h4>Introduction</h4> Acute plaque rupture or erosion followed by luminal thrombosis is a major cause of myocardial infarction and sudden cardiac death. Vulnerable plaques are characterized by a thin fibrous cap and reduced numbers of smooth muscle cells (SMCs). SMCs are essential for plaque stability, as they synthesize collagen and support fibrous cap structure. Our previous work demonstrated that insulin-like...

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Literature Corpus work: 235ec1ff-173b-5524-8a90-83d9bdecbe1d
DOI: 10.64898/2025.12.22.696106

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