Article
Exosomes: mediators regulating the phenotypic transition of vascular smooth muscle cells in atherosclerosis.
Cell communication and signaling : CCS - 11 Oct 2022
Yao Jiali, Cai Linqian, Chen Yingrui, Zhang Jie, Zhuang Wenwen, Liang Jingyan, Li Hongliang
Abstract excerpt
Cardiovascular disease is one of the leading causes of human mortality worldwide, mainly due to atherosclerosis (AS), and the phenotypic transition of vascular smooth muscle cells (VSMCs) is a key event in the development of AS. Exosomes contain a variety of specific nucleic acids and proteins that mediate intercellular communication. The role of exosomes in AS has attracted attention. This review uses the VSMC...
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