tRNA-derived small RNAs in vascular smooth muscle cell phenotypic switching and vascular remodelling.

Abstract excerpt

tRNA-derived small RNAs (tsRNAs) are noncoding RNAs generated from precursor or mature tRNAs. Basal tsRNA levels are detectable under physiological conditions, but their production increases sharply under cellular stress. tsRNAs regulate gene expression through miRNA-like targeting, translational control, and intercellular communication. In vascular remodelling disorders-including atherosclerosis (AS), aortic...

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• Share to Atherosclerosis
• Share to Hypertension, Pulmonary
• Share to MicroRNAs
• Share to Muscle, Smooth, Vascular
• Share to Myocytes, Smooth Muscle
• Share to RNA, Small Untranslated
• Share to RNA, Transfer
• Share to Vascular Remodeling