Article

The Repertoire of Mutational Signatures in Human Cancer

2018-05-15

Abstract excerpt

<h4>ABSTRACT</h4> Somatic mutations in cancer genomes are caused by multiple mutational processes each of which generates a characteristic mutational signature. Using 84,729,690 somatic mutations from 4,645 whole cancer genome and 19,184 exome sequences encompassing most cancer types we characterised 49 single base substitution, 11 doublet base substitution, four clustered base substitution, and 17 small insertio...

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Literature Corpus work: 7aee2922-8e15-551d-a58d-e1909010b3dc
DOI: 10.1101/322859

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