Article

MutSpot: detection of non-coding mutation hotspots in cancer genomes

2019-08-20

Abstract excerpt

<h4>Summary</h4> Recurrence and clustering of somatic mutations (hotspots) in cancer genomes may indicate positive selection and involvement in tumorigenesis. MutSpot performs genome-wide inference of mutation hotspots in non-coding and regulatory DNA of cancer genomes. MutSpot performs feature selection across hundreds of epigenetic and sequence features followed by estimation of position and patient-specific ba...

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Literature Corpus work: 950ef699-bd7b-5ede-aa1e-f976a8a7c38e
DOI: 10.1101/740944

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