Article

OncodriveCLUSTL: a sequence-based clustering method to identify cancer drivers

2018-12-19

Abstract excerpt

<h4>Summary</h4> The identification of the genomic alterations driving tumorigenesis is one of the main goals in oncogenomics research. Given the evolutionary principles of cancer development, computational methods that detect signals of positive selection in the pattern of tumor mutations have been effectively applied in the search for cancer genes. One of these signals is the abnormal clustering of mutations, w...

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Literature Corpus work: fbea15a9-35ce-59db-a79b-7ad2f52400a5
DOI: 10.1101/500132

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