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Article

Xenoline-polarized macrophages as a physiologically relevant in vitro model of tumor- associated macrophages in glioblastoma

2025-05-09

Abstract excerpt

<title>Abstract</title> <p>Tumor-associated macrophages (TAMs) are the most abundant non-cancerous cell type in glioblastoma (GBM) and heavily influence GBM biology, contributing to tumor progression, therapeutic resistance, immune evasion, and neovascularization. Current <italic>in vitro</italic> models that utilize IL-4/IL-13 stimulation fail to capture the transcriptional and functional heterogeneity of TAMs o...

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Literature Corpus work
ef07e81e-2bc7-53ea-83bf-a75d131cf399
DOI
10.21203/rs.3.rs-6567445/v1
Open publication

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Xenoline-polarized macrophages as a physiologically relevant in vitro model of tumor- associated macrophages in glioblastomaDOI 10.21203/rs.3.rs-6567445/v1
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