Article

Single-cell transcriptomics reveals immunosuppressive microenvironment and highlights stumor-promoting macrophage cells in Glioblastoma

2024-06-10

Abstract excerpt

<title>Abstract</title> <p>Purpose Glioblastoma (GBM) is the most prevalent and aggressive primary brain malignancy in adults. Nevertheless, the cellular heterogeneity and complexity within the GBM microenvironment (TME) are still not fully understood, posing a significant obstacle in the advancement of more efficient immunotherapies for GBM. Methods In this study, we conducted an integrated analysis of 48 tumo...

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Literature Corpus work: fc9d9733-c597-5da7-9f7e-7649772910b0
DOI: 10.21203/rs.3.rs-4457641/v1

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