Article

Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice

2021-12-16

Abstract excerpt

Cancer survivors suffer from progressive frailty, multimorbidity and premature morbidity. We hypothesize that therapy-induced senescence and senescence progression via bystander effects is a significant cause of this premature ageing phenotype. Accordingly, the study addresses the question whether a short anti-senescence intervention is able to block progression of radiation-induced frailty and disability in a pre...

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Literature Corpus work: eefb9a20-7517-5124-b98f-7feb12094afa
DOI: 10.1101/2021.12.15.472756

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