Article
Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction.
Advances in protein chemistry and structural biology - 1 Jan 2023
Nehlin Jan O
Abstract excerpt
The accumulation of senescent cells in the aging individual is associated with an increase in the occurrence of age-associated pathologies that contribute to poor health, frailty, and mortality. The number and type of senescent cells is viewed as a contributor to the body's senescence burden. Cellular models of senescence are based on induction of senescence in cultured cells in the laboratory. One type of...
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