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Clinical Trials Targeting Aging

4 Feb 2022

Abstract excerpt

The risk of morbidity and mortality increases exponentially with age. Chronic inflammation, accumulation of DNA damage, dysfunctional mitochondria, and increased senescent cell load are factors contributing to this. Mechanistic investigations have revealed specific pathways and processes which, proposedly, cause age-related phenotypes such as frailty, reduced physical resilience, and multi-morbidity. Among...

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PMID: 35821843
DOI: 10.3389/fragi.2022.820215

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