Article
Cellular senescence and frailty: a comprehensive insight into the causal links.
GeroScience - 1 Dec 2023
Marcozzi Serena, Bigossi Giorgia, Giuliani Maria Elisa, Giacconi Robertina, Piacenza Francesco, Cardelli Maurizio, Brunetti Dario, Segala Agnese, Valerio Alessandra, Nisoli Enzo, Lattanzio Fabrizia, Provinciali Mauro, Malavolta Marco
Abstract excerpt
Senescent cells may have a prominent role in driving inflammation and frailty. The impact of cellular senescence on frailty varies depending on the assessment tool used, as it is influenced by the criteria or items predominantly affected by senescent cells and the varying weights assigned to these items across different health domains. To address this challenge, we undertook a thorough review of all available...
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