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Senotherapeutics and Their Molecular Mechanism for Improving Aging

13 Oct 2022

Abstract excerpt

Aging is defined as physiological dysfunction of the body and a key risk factor for human diseases. During the aging process, cellular senescence occurs in response to various extrinsic and intrinsic factors such as radiation-induced DNA damage, the activation of oncogenes, and oxidative stress. These senescent cells accumulate in many tissues and exhibit diverse phenotypes, such as resistance to apoptosis,...

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Share to Circadian rhythm and melatonin
Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 36226551
DOI: 10.4062/biomolther.2022.114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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