Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Senolytics (DQ) Mitigates Radiation Ulcers by Removing Senescent Cells

14 Feb 2020

Abstract excerpt

Radiation ulcers are a prevalent toxic side effect in patients receiving radiation therapy. At present, there is still no effective treatment for the complication. Senescent cells accumulate after radiation exposure, which can induce cell and tissue dysfunction. Here we demonstrate increased expression of p16 (a senescence biomarker) in human radiation ulcers after radiotherapy and radiation-induced persistent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to NF-κB Signaling Pathways
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32117790
DOI: 10.3389/fonc.2019.01576

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Senolytics (DQ) Mitigates Radiation Ulcers by Removing Senescent CellsPMID 32117790Read ↗

Radiation-induced senescence: therapeutic opportunitiesSemantic proximity Read ↗

Zileuton Alleviates Radiation-Induced Cutaneous Ulcers via Inhibition of Senescence-Associated Secretory Phenotype in Rodents.Semantic proximity Read ↗

Senescence Modulation: An Applied Science Review of Strategies in Anti-Aging, Regenerative Aesthetics, and Oncology TherapySemantic proximity Read ↗

Senotherapeutics and Their Molecular Mechanism for Improving AgingSemantic proximity Read ↗

Senescence Modulation: An Applied Science Review of Strategies in Anti-Aging, Regenerative Aesthetics, and Oncology TherapySemantic proximity Read ↗

Molecular Regulation of SASP in Cellular Senescence: Therapeutic Implications and Translational ChallengesSemantic proximity Read ↗

Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell nicheSemantic proximity Read ↗

Targeting senescence as an anticancer therapySemantic proximity Read ↗

Targeting senescence‐associated secretory phenotypes to remodel the tumour microenvironment and modulate tumour outcomesSemantic proximity Read ↗

Regulation of cellular senescence in tumor progression and therapeutic targeting: mechanisms and pathwaysSemantic proximity Read ↗

Senolytics: A Translational Bridge Between Cellular Senescence and Organismal AgingSemantic proximity Read ↗

Aging and oral squamous cell carcinoma development: the role of cellular senescenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.