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A second generation of senotherapies: the development of targeted senolytics, senoblockers and senoreversers for healthy ageing

28 Jun 2024

Abstract excerpt

Cellular senescence, a form of terminal cell cycle arrest, is as a key driver of organismal ageing and an important factor in age-related diseases. Insights into the senescent phenotype have led to the development of novel therapeutic strategies, collectively known as senotherapies, that aim to ameliorate the detrimental effects of senescent cell accumulation in tissues. The senotherapeutic field has rapidly...

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Share to Advanced biosensing and bioanalysis techniques
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38940746
DOI: 10.1042/bst20231066

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