Article

Hotspot of <i>de novo</i> telomere addition stabilizes linear amplicons in yeast grown in sulfate-limiting conditions

2022-06-15

Abstract excerpt

Evolution is driven by the accumulation of competing mutations that influence survival. A broad form of genetic variation is the amplification or deletion of DNA (≥50 bp) referred to as copy number variation. In humans, copy number variation may be inconsequential, contribute to minor phenotypic differences, or cause conditions such as birth defects, neurodevelopmental disorders, and cancers. To identify mechanism...

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Literature Corpus work: eed1467e-8f20-5188-8cd5-9f578703aa56
DOI: 10.1101/2022.06.12.495855

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