Article
The dynamics of diverse segmental amplifications in populations of Saccharomyces cerevisiae adapting to strong selection.
G3 (Bethesda, Md.) - 20 Mar 2014
Payen Celia, Di Rienzi Sara C, Ong Giang T, Pogachar Jamie L, Sanchez Joseph C, Sunshine Anna B, Raghuraman M K, Brewer Bonita J, Dunham Maitreya J
Abstract excerpt
Population adaptation to strong selection can occur through the sequential or parallel accumulation of competing beneficial mutations. The dynamics, diversity, and rate of fixation of beneficial mutations within and between populations are still poorly understood. To study how the mutational landscape varies across populations during adaptation, we performed experimental evolution on seven parallel populations of...
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