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Article

Conserved enhancer association of piRNAs and the implication in germ cell fate surveillance

2025-06-25

Abstract excerpt

<title>Abstract</title> <p>The PIWI-piRNA pathway is crucial for protecting genomic integrity from derepressed transposon invasion in developing germ cells after genome-wide epigenetic erasure. Extensive mouse studies show that pre-pachytene piRNAs contribute to establishing the epigenetic landscape. However, little is known about human piRNAs during embryonic fetal germ cell development. In this study, we collec...

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Literature Corpus work
eec76073-f93e-5487-9901-46128a47711d
DOI
10.21203/rs.3.rs-6314689/v1
Open publication

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Conserved enhancer association of piRNAs and the implication in germ cell fate surveillanceDOI 10.21203/rs.3.rs-6314689/v1
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