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Article

piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells.

Genes & development - 1 Jul 2014

Pezic Dubravka, Manakov Sergei A, Sachidanandam Ravi, Aravin Alexei A

Abstract excerpt

Transposable elements (TEs) occupy a large fraction of metazoan genomes and pose a constant threat to genomic integrity. This threat is particularly critical in germ cells, as changes in the genome that are induced by TEs will be transmitted to the next generation. Small noncoding piwi-interactin...

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Identifiers

PMID: 24939875
DOI: 10.1101/gad.240895.114
PMCID: PMC4083086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24939875-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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