Article

Integrated small and long RNA sequencing in single oocytes reveals piRNA-mediated transposon repression during human oogenesis

2025-07-26

Abstract excerpt

The piwi-interacting RNA (piRNA) pathway plays a pivotal role in controlling transposable element (TE) activity, which is crucial for the developmental competence of gametogenesis. Although piRNAs have been studied in golden hamsters and other representative mammals, little is known about the relationship between distinct piRNA populations and their regulatory effects on TEs in human oocytes. In this study, we sim...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f4a34a24-2f8b-5706-8cd1-b36c96d71dff
DOI: 10.1101/2025.07.22.666229

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Integrated small and long RNA sequencing in single oocytes reveals piRNA-mediated transposon repression during human oogenesisDOI 10.1101/2025.07.22.666229Read

piRNA pathway is essential for generating functional oocytes in golden hamsterSemantic proximity Read

A comprehensive analysis of piRNAs from adult human testis and their relationship with genes and mobile elementsSemantic proximity Read

PIWIL3-piRNA Pathway Is Essential for Rabbit Oogenesis and Embryogenesis via Broad Regulation of the Transcriptome and ProteomeSemantic proximity Read

Conserved enhancer association of piRNAs and the implication in germ cell fate surveillanceSemantic proximity Read

Conserved small nucleotidic elements at the origin of concerted piRNA biogenesis from genes and lncRNAsSemantic proximity Read

Pachytene piRNAs define a conserved program of meiotic gene regulationSemantic proximity Read

Production of functional oocytes requires maternally expressed <i>PIWI</i> genes and piRNAs in golden hamstersSemantic proximity Read

Pachytene piRNAs define a conserved program of meiotic gene regulationSemantic proximity Read

The single-cell expression profile of transposable elements and transcription factors in human early biparental and uniparental embryonic developmentSemantic proximity Read

Golden hamster piRNAs are necessary for early embryonic development and establishment of spermatogoniaSemantic proximity Read

Nonredundant functions for Aedes albopictus Piwi5 in piRNA biogenesis and transposon silencingSemantic proximity Read

A burst of transposon expression accompanies the activation of Y chromosome fertility genes during Drosophila spermatogenesisSemantic proximity Read