Article

A somatic piRNA pathway regulates epithelial-to-mesenchymal transition of chick neural crest cells

2021-04-30

Abstract excerpt

In the metazoan germline, Piwi proteins play an essential regulatory role in maintenance of stemness and self-renewal by piRNA-mediated repression of transposable elements. To date, the activity of Piwi proteins and the piRNA pathway in vertebrates was believed to be confined to the gonads. Our results reveal expression of Piwil1 in a vertebrate somatic cell type, the neural crest–a migratory embryonic stem cell p...

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Literature Corpus work: cdfbf0c3-8565-537b-8523-29adfb442612
DOI: 10.1101/2021.04.30.442165

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