Article

Schizophrenia hiPSC neurons display expression changes that are enriched for disease risk variants and a blunted activity-dependent response

2016-07-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>IMPORTANCE</h4> Schizophrenia (SCZ) is a common illness with complex genetic architecture where both common genetic variation and rare mutations have been implicated. SCZ candidate genes participate in common molecular pathways that are regulated by activity-dependent changes in neurons, including the signaling network that modulates synaptic strength and the network of genes that are targe...

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Literature Corpus work: ee88873b-3a75-54b4-80ca-e425ad7ae28c
DOI: 10.1101/062885

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