Article

Single-cell multi-cohort dissection of the schizophrenia transcriptome

2022-09-02

Abstract excerpt

Schizophrenia is a prevalent mental illness with a high societal burden, complex pathophysiology, and diverse genetic and environmental etiology. Its complexity, polygenicity, and heterogeneity have hindered mechanistic elucidation and the search for new therapeutics. We present a single-cell dissection of schizophrenia-associated transcriptomic changes in the human prefrontal cortex across two independent cohorts...

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Literature Corpus work: ed81f095-2e40-5fa1-b745-4a55dd97549f
DOI: 10.1101/2022.08.31.22279406

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