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Article

Activity-Dependent Changes in Gene Expression in Schizophrenia Human-Induced Pluripotent Stem Cell Neurons.

JAMA psychiatry - 1 Nov 2016

Roussos Panos, Guennewig Boris, Kaczorowski Dominik C, Barry Guy, Brennand Kristen J

Abstract excerpt

IMPORTANCE: Schizophrenia candidate genes participate in common molecular pathways that are regulated by activity-dependent changes in neurons. One important next step is to further our understanding on the role of activity-dependent changes of gene expression in the etiopathogenesis of schizophrenia. OBJECTIVE: To examine whether neuronal activity-dependent changes of gene expression are dysregulated in...

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Identifiers

PMID: 27732689
DOI: 10.1001/jamapsychiatry.2016.2575
PMCID: PMC5437975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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