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An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals

2023-10-18

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<title>Abstract</title> <p>Genome wide association studies (GWAS) have identified over 100 signals associated with type 1 diabetes (T1D). However, translating any given T1D GWAS signal into mechanistic insights, such as causal variants, their target genes, and the specific cell types involved, has been challenging. Here, we present a comprehensive multi-omic integrative analysis of single-cell/nucleus resolution...

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Literature Corpus work
ee519cd9-3a12-5b14-afe8-8f6f1ed6e9cb
DOI
10.21203/rs.3.rs-3343318/v1
Open publication

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An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signalsDOI 10.21203/rs.3.rs-3343318/v1
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