Article

Integration of GWAS-Derived Polygenic Risk Scores with Single-Cell RNA Sequencing to Identify Cell-Type–Specific Genetic Risk in Type 2 Diabetes.

2026-04-14

Abstract excerpt

<title>Abstract</title> <p>Type 2 Diabetes (T2D) is a complicated disease, influenced by both genetic factors and cellular dysfunction inside the pancreatic tissue. Over the years, researchers have identified many genetic variants associated with T2D risk through Genome Wide Association Studies (GWAS), but it’s still tough to determine exactly how these variants affect different cell types. This study introduces...

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Literature Corpus work: dfaa9091-5731-567d-b6b0-328ac686804b
DOI: 10.21203/rs.3.rs-9396739/v1

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