Article

Generalizing Genetic Risk Scores from Europeans to Hispanics/Latinos

2018-01-04

Abstract excerpt

Genetic risk scores (GRSs) are weighted sums of risk allele counts of single nucleotide polymorphisms (SNPs) associated with a disease or trait. Construction of GRSs is typically based on published results from Genome-Wide Association Studies (GWASs), the majority of which have been performed in large populations of European ancestry (EA) individuals. While many genotype-trait associations have been shown to gener...

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Literature Corpus work: edb818f9-6cdb-51ee-a0c2-3eabbd323668
DOI: 10.1101/242404

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