Article
Development and evaluation of a genetic risk score for obesity.
Biodemography and social biology - 1 Jan 2013
Belsky Daniel W, Moffitt Terrie E, Sugden Karen, Williams Benjamin, Houts Renate, McCarthy Jeanette, Caspi Avshalom
Abstract excerpt
Multi-locus profiles of genetic risk, so-called "genetic risk scores," can be used to translate discoveries from genome-wide association studies into tools for population health research. We developed a genetic risk score for obesity from results of 16 published genome-wide association studies of obesity phenotypes in European-descent samples. We then evaluated this genetic risk score using data from the...
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