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Article

Genetic association analysis under complex survey sampling: the Hispanic Community Health Study/Study of Latinos.

American journal of human genetics - 4 Dec 2014

Lin Dan-Yu, Tao Ran, Kalsbeek William D, Zeng Donglin, Gonzalez Franklyn, Fernández-Rhodes Lindsay, Graff Mariaelisa, Koch Gary G, North Kari E, Heiss Gerardo

Abstract excerpt

The cohort design allows investigators to explore the genetic basis of a variety of diseases and traits in a single study while avoiding major weaknesses of the case-control design. Most cohort studies employ multistage cluster sampling with unequal probabilities to conveniently select participants with desired characteristics, and participants from different clusters might be genetically related. Analysis that...

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Identifiers

PMID: 25480034
DOI: 10.1016/j.ajhg.2014.11.005
PMCID: PMC4259979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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