Article

Chronic Jetlag Accelerates Pancreatic Neoplasia in Conditional <i>Kras</i> -Mutant Mice

2022-07-19

Abstract excerpt

Misalignment of the circadian clock compared to environmental cues causes circadian desynchrony, which is pervasive in humans. Clock misalignment can lead to various pathologies including obesity and diabetes, both of which are associated with pancreatic ductal adenocarcinoma - a devastating cancer with an 80% five-year mortality rate. Although circadian desynchrony is associated with an increased risk of several...

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Literature Corpus work: ed267aa9-f647-5655-a916-bdc91e02be85
DOI: 10.1101/2022.07.18.500370

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