Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circadian Rhythm Disruption Promotes Lung Tumorigenesis.

Cell metabolism - 9 Aug 2016

Papagiannakopoulos Thales, Bauer Matthew R, Davidson Shawn M, Heimann Megan, Subbaraj Lakshmipriya, Bhutkar Arjun, Bartlebaugh Jordan, Vander Heiden Matthew G, Jacks Tyler

Abstract excerpt

Circadian rhythms are 24-hr oscillations that control a variety of biological processes in living systems, including two hallmarks of cancer, cell division and metabolism. Circadian rhythm disruption by shift work is associated with greater risk for cancer development and poor prognosis, suggesting a putative tumor-suppressive role for circadian rhythm homeostasis. Using a genetically engineered mouse model of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glucose
Share to Lung
Share to Lung Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Circadian Rhythm

Share to Adenocarcinoma

Share to Cell Transformation, Neoplastic

Share to Mice, Inbred C57BL

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 27476975
DOI: 10.1016/j.cmet.2016.07.001
PMCID: PMC5367626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circadian Rhythm Disruption Promotes Lung Tumorigenesis.PMID 27476975Read ↗

The Cancer Clock Is (Not) Ticking: Links between Circadian Rhythms and CancerSemantic proximity Read ↗

Circadian Rhythm Disruption in Cancer BiologySemantic proximity Read ↗

Circadian Clock Manipulation for Cancer Prevention and Control and the Relief of Cancer SymptomsSemantic proximity Read ↗

Circadian disruption does not alter tumorigenesis in a mouse model of lymphomaSemantic proximity Read ↗

Roles of circadian clocks in cancer pathogenesis and treatmentSemantic proximity Read ↗

Circadian molecular clock disruption in chronic pulmonary diseasesSemantic proximity Read ↗

The Relationship between Circadian Rhythm and Cancer DiseaseSemantic proximity Read ↗

Modulatory Effects of Circadian Rhythms in the Lung Adenocarcinoma Tumor MicroenvironmentSemantic proximity Read ↗

Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancerSemantic proximity Read ↗

The Common Hallmarks and Interconnected Pathways of Aging, Circadian Rhythms, and Cancer: Implications for Therapeutic StrategiesSemantic proximity Read ↗

Cancer Clocks Out for Lunch: Disruption of Circadian Rhythm and Metabolic Oscillation in CancerSemantic proximity Read ↗

Major roles of the circadian clock in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.