Article

Single-Cell RNA-Seq Analysis Reveals Four Stages of Replicative Senescence in Human Umbilical Vein Endothelial Cells

2023-11-15

Abstract excerpt

Cellular senescence is a phenomenon marked by an irreversible growth arrest with altered physiological properties. Many studies have focused on the characteristics of cells that have already entered a senescent state. However, to elucidate the mechanisms of cellular aging, it is essential to investigate the gradual transition of proliferative cells into senescent cells. We assumed that cellular senescence is a com...

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Literature Corpus work: ec7d0760-473e-5202-93a0-1d3f3c5bd4a4
DOI: 10.1101/2023.11.12.566783

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