Article

<i>SenePy</i> : Unveiling the Cell-Type Specific Landscape of Cellular Senescence through Single-Cell Analysis in Living Organisms

2023-08-31

Abstract excerpt

<h4>ABSTRACT</h4> Senescent cells accumulate in tissues with organismal age and contribute causally to multiple chronic diseases. In vivo senescent cell phenotypes are heterogeneous because cellular context and stressors vary by cell type and tissue. Due to the variability of senescence programs, there is no universal method to identify senescent cells and even widely used markers, such as CDKN2A , are not ubiq...

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Literature Corpus work: 4a6f9c71-5196-54fe-a928-faddf7b93e62
DOI: 10.1101/2023.08.30.555644

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