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Integrated multi-omics approach revealed cellular senescence landscape

1 Oct 2022

Abstract excerpt

Cellular senescence is a complex multifactorial biological phenomenon that plays essential roles in aging, and aging-related diseases. During this process, the senescent cells undergo gene expression altering and chromatin structure remodeling. However, studies on the epigenetic landscape of senescence using integrated multi-omics approaches are limited. In this research, we performed ATAC-seq, RNA-seq and...

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Share to Genomics and Chromatin Dynamics
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PMID: 36243980
DOI: 10.1093/nar/gkac885

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