Article

Gene Regulatory Network Analysis Defines Transcriptome Landscape with Alternative Splicing of Human Umbilical Vein Endothelial Cells during Replicative Senescence

2021-01-12

Abstract excerpt

<h4>Background: </h4> Endothelial cell senescence is the state of permanent cell cycle arrest and plays a critical role in the pathogenesis of age-related diseases. However, a comprehensive understanding of the gene regulatory network, including genome-wide alternative splicing machinery, involved in endothelial cell senescence is lacking. <h4>Results: </h4> We thoroughly described the transcriptome landscape of r...

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Literature Corpus work: 6d20dfec-a668-5f64-a1f2-c8f0060a8ab1
DOI: 10.21203/rs.3.rs-140983/v1

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