Article

Decoding neuronal diversity by single-cell Convert-seq

2019-04-05

Abstract excerpt

<h4>Summary</h4> The conversion of cell fates is controlled by hierarchical gene regulatory networks (GRNs) that induce remarkable alterations in cellular and transcriptome states. The identification of key regulators within these networks from myriad of candidate genes, however, poses a major research challenge. Here we present Convert-seq, combining single-cell RNA sequencing (scRNA-seq) and pooled ectopic gene...

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Literature Corpus work: ec55a21a-0804-57f4-aed6-71b1f4d26a71
DOI: 10.1101/600239

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