Article

CellRegMap: A statistical framework for mapping context-specific regulatory variants using scRNA-seq

2021-09-02

Abstract excerpt

Single cell RNA sequencing (scRNA-seq) enables characterizing the cellular heterogeneity in human tissues. Technological advances have enabled the first population-scale scRNA-seq studies in hundreds of individuals, allowing to assay genetic effects with single-cell resolution. However, existing strategies to perform genetic analyses using scRNA-seq remain based on principles established for bulk RNA-seq. In parti...

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Literature Corpus work: b59a1f18-ba7f-5c16-932f-9408b4829283
DOI: 10.1101/2021.09.01.458524

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