Article

Refate identifies chemical compounds to target trans-regulatory networks for cellular conversion

2025-07-12

Abstract excerpt

<h4>ABSTRACT</h4> Identifying chemical compounds that target trans-regulatory networks (TRNs) underlying molecular programs of cells for directed cellular conversion (i.e. differentiation, reprogramming, transdifferentiation, and dedifferentiation) is a key step towards advancing regenerative medicine. Recent innovations in single-cell omics technologies enabled high-resolution profiling of TRNs that govern cell...

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Literature Corpus work: 295f1c04-ccf5-5d4e-8a2c-62a84aafbf5b
DOI: 10.1101/2025.07.09.664003

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