Article

Expanding GABAergic Neuronal Diversity in PSC-Derived Disease Models

2024-12-04

Abstract excerpt

<h4>SUMMARY</h4> GABAergic interneurons comprise diverse molecular and functional subtypes that contribute to neural circuit assembly and are implicated in a range of neurodevelopmental and neuropsychiatric disorders. Traditional approaches for differentiating human pluripotent stem cells (PSCs) into neurons often face challenges such as incomplete neural differentiation, prolonged culture periods, and variabilit...

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Literature Corpus work: 6ff3c3a4-eb1f-5905-be4e-aa564351ebfc
DOI: 10.1101/2024.12.03.626438

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